Obesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity

Abstract Background Obesity is correlated with an increased risk for developing postmenopausal breast cancer. Since obesity rates continue to rise worldwide, it is important to understand how the obese microenvironment influences normal mammary tissue to increase breast cancer risk. We hypothesized...

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Bibliographic Details
Main Authors: Tamara Chamberlin, Joseph V. D’Amato, Lisa M. Arendt
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Breast Cancer Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13058-017-0921-7