Obesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity
Abstract Background Obesity is correlated with an increased risk for developing postmenopausal breast cancer. Since obesity rates continue to rise worldwide, it is important to understand how the obese microenvironment influences normal mammary tissue to increase breast cancer risk. We hypothesized...
Main Authors: | Tamara Chamberlin, Joseph V. D’Amato, Lisa M. Arendt |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-11-01
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Series: | Breast Cancer Research |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13058-017-0921-7 |
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