P4.32 INACTIVATION OF SERUM RESPONSE FACTOR CONTRIBUTES TO DECREASE VASCULAR MUSCULAR TONE AND ARTERIAL STIFFNESS IN MICE
Rationale: Vascular smooth muscle cell (VSMC) phenotypic modulation plays an important role in arterial stiffening associated with ageing. Serum response factor (SRF) is a major transcription factor regulating smooth muscle (SM) genes involved in maintenance of the contractile state of VSMCs. Objec...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Atlantis Press
2013-11-01
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| Series: | Artery Research |
| Online Access: | https://www.atlantis-press.com/article/125939035/view |