Renal scar formation and kidney function following antibiotic-treated murine pyelonephritis

Renal scar formation and kidney function following antibiotic-treated murine pyelonephritis

We present a new preclinical model to study treatment, resolution and sequelae of severe ascending pyelonephritis. Urinary tract infection (UTI), primarily caused by uropathogenic Escherichia coli (UPEC), is a common disease in children. Severe pyelonephritis is the primary cause of acquired renal s...

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Bibliographic Details
Main Authors: Patrick D. Olson, Lisa K. McLellan, Alice Liu, Kelleigh L. Briden, Kristin M. Tiemann, Allyssa L. Daugherty, Keith A. Hruska, David A. Hunstad
Format: Article
Language:English
Published: The Company of Biologists 2017-11-01
Series:Disease Models & Mechanisms
Subjects:
Pyelonephritis
Renal scarring
Fibrosis
Urinary tract infection
Chronic kidney disease
Hydronephrosis
Online Access:http://dmm.biologists.org/content/10/11/1371

Internet

http://dmm.biologists.org/content/10/11/1371

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