Open chromatin dynamics reveals stage-specific transcriptional networks in hiPSC-based neurodevelopmental model

Open chromatin dynamics reveals stage-specific transcriptional networks in hiPSC-based neurodevelopmental model

Chromatin accessibility to transcription factors (TFs) strongly influences gene transcription and cell differentiation. However, a mechanistic understanding of the transcriptional control during the neuronal differentiation of human induced pluripotent stem cells (hiPSCs), a promising cellular model...

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Bibliographic Details
Main Authors: Siwei Zhang, Winton Moy, Hanwen Zhang, Catherine Leites, Heather McGowan, Jianxin Shi, Alan R. Sanders, Zhiping P. Pang, Pablo V. Gejman, Jubao Duan
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506118300928

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http://www.sciencedirect.com/science/article/pii/S1873506118300928

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