Cancer Immunotherapy Using Chimeric Antigen Receptor Expressing T-Cells: Present and Future Needs of Clinical Cancer Centers

Chimeric Antigen Receptor-T cells (CAR-T) are considered novel biological agents, designed to selectively attack cancer cells expressing specific antigens, with demonstrated clinical activity in patients affected with relapsed/refractory B-cell malignancies. In consideration of their complexity, the...

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Bibliographic Details
Main Authors: Manuel Gotti, Irene Defrancesco, Mario D’Angelo, Sabrina Basso, Luca Crotto, Alfredo Marinelli, Cristina Maccalli, Vincenzo Iaconianni
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
GMP
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.565236/full