Dual function of the NK cell receptor 2B4 (CD244) in the regulation of HCV-specific CD8+ T cells.

Dual function of the NK cell receptor 2B4 (CD244) in the regulation of HCV-specific CD8+ T cells.

The outcome of viral infections is dependent on the function of CD8+ T cells which are tightly regulated by costimulatory molecules. The NK cell receptor 2B4 (CD244) is a transmembrane protein belonging to the Ig superfamily which can also be expressed by CD8+ T cells. The aim of this study was to a...

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Bibliographic Details
Main Authors: Verena Schlaphoff, Sebastian Lunemann, Pothakamuri Venkata Suneetha, Jerzy Jaroszewicz, Jan Grabowski, Julia Dietz, Fabian Helfritz, Hueseyin Bektas, Christoph Sarrazin, Michael Peter Manns, Markus Cornberg, Heiner Wedemeyer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3098233?pdf=render

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http://europepmc.org/articles/PMC3098233?pdf=render

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