Designing of highly effective complementary and mismatch siRNAs for silencing a gene.

In past, numerous methods have been developed for predicting efficacy of short interfering RNA (siRNA). However these methods have been developed for predicting efficacy of fully complementary siRNA against a gene. Best of author's knowledge no method has been developed for predicting efficacy...

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Bibliographic Details
Main Authors: Firoz Ahmed, Gajendra P S Raghava
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21853133/?tool=EBI