A novel LRP6 variant in a Japanese family with oligodontia

A novel LRP6 variant in a Japanese family with oligodontia

Abstract Congenital tooth agenesis is a common anomaly in human development. We performed exome sequence analysis of genomic DNA collected from Japanese patients with tooth agenesis and their relatives. We found a novel single-nucleotide insertion in the LRP6 gene, the product of which is involved i...

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Bibliographic Details
Main Authors: Hiroki Goto, Masashi Kimura, Junichiro Machida, Akiko Ota, Mitsuko Nakashima, Naomi Tsuchida, Junya Adachi, Yoshihiko Aoki, Tadashi Tatematsu, Katsu Takahashi, Masatoshi Sana, Atsuo Nakayama, Shintaro Suzuki, Toru Nagao, Naomichi Matsumoto, Yoshihito Tokita
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Human Genome Variation
Online Access:https://doi.org/10.1038/s41439-021-00162-w

Internet

https://doi.org/10.1038/s41439-021-00162-w

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