Nano-mediated delivery of double-stranded RNA for gene therapy of glioblastoma multiforme.

Glioblastoma multiforme (GBM) is the most common type of malignant gliomas, characterized by genetic instability, intratumoral histopathological variability and unpredictable clinical behavior. Disappointing results in the treatment of gliomas with surgery, radiation and chemotherapy have fueled a s...

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Bibliographic Details
Main Authors: Małgorzata Grabowska, Bartosz F Grześkowiak, Kosma Szutkowski, Dariusz Wawrzyniak, Paweł Głodowicz, Jan Barciszewski, Stefan Jurga, Katarzyna Rolle, Radosław Mrówczyński
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0213852