A paclitaxel and microRNA-124 coloaded stepped cleavable nanosystem against triple negative breast cancer

A paclitaxel and microRNA-124 coloaded stepped cleavable nanosystem against triple negative breast cancer

Abstract Background Triple negative breast cancer (TNBC) is one of the most biologically aggressive breast cancers and lacks effective treatment options, resulting in a poor prognosis. Therefore, studies aiming to explore new therapeutic strategies for advanced TNBC are urgently needed. According to...

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Bibliographic Details
Main Authors: Chuanrong Chen, Ming Shen, Hongze Liao, Qianqian Guo, Hao Fu, Jian Yu, Yourong Duan
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Journal of Nanobiotechnology
Subjects:
Stepped cleavable nanoparticles
Paclitaxel
MicroRNA-124
Synergistic antitumour effect
Triple negative breast cancer
Online Access:https://doi.org/10.1186/s12951-021-00800-z

Internet

https://doi.org/10.1186/s12951-021-00800-z

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