Epigenetic Heterogeneity of B-Cell Lymphoma: DNA Methylation, Gene Expression and Chromatin States

Epigenetic Heterogeneity of B-Cell Lymphoma: DNA Methylation, Gene Expression and Chromatin States

Mature B-cell lymphoma is a clinically and biologically highly diverse disease. Its diagnosis and prognosis is a challenge due to its molecular heterogeneity and diverse regimes of biological dysfunctions, which are partly driven by epigenetic mechanisms. We here present an integrative analysis of D...

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Bibliographic Details
Main Authors: Lydia Hopp, Henry Löffler-Wirth, Hans Binder
Format: Article
Language:English
Published: MDPI AG 2015-09-01
Series:Genes
Subjects:
germinal center
epigenetic reprogramming
stemness
promoter methylation
gene expression
machine learning
high dimensional data portraying
Online Access:http://www.mdpi.com/2073-4425/6/3/812

Internet

http://www.mdpi.com/2073-4425/6/3/812

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