Synthesis and Physicochemical Characterization of the Impurities of Pemetrexed Disodium, an Anticancer Drug

A physicochemical characterization of the process-related impurities associated with the synthesis of pemetrexed disodium was performed. The possibility of pemetrexed impurities forming has been mentioned in literature, but no study on their structure has been published yet. This paper describes the...

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Bibliographic Details
Main Authors: Olga Michalak, Mariusz M. Gruza, Anna Witkowska, Iwona Bujak, Piotr Cmoch
Format: Article
Language:English
Published: MDPI AG 2015-05-01
Series:Molecules
Subjects:
NMR
Online Access:http://www.mdpi.com/1420-3049/20/6/10004