Chronic BACE-1 Inhibitor Administration in TASTPM Mice (APP KM670/671NL and PSEN1 M146V Mutation): An EEG Study

Chronic BACE-1 Inhibitor Administration in TASTPM Mice (APP KM670/671NL and PSEN1 M146V Mutation): An EEG Study

Objective. In this exploratory study, we tested whether electroencephalographic (EEG) rhythms may reflect the effects of a chronic administration (4 weeks) of an anti-amyloid β-site amyloid precursor protein (APP) cleaving enzyme 1 inhibitor (BACE-1; ER-901356; Eisai Co., Ltd., Tokyo, Japan) in TAST...

Full description

Bibliographic Details
Main Authors: Susanna Lopez, Claudio Del Percio, Gianluigi Forloni, Angelisa Frasca, Wilhelmus H. Drinkenburg, Roberta Lizio, Giuseppe Noce, Raffaele Ferri, Andrea Soricelli, Fabrizio Stocchi, Laura Vacca, Règis Bordet, Jill C. Richardson, Claudio Babiloni
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
electroencephalography (EEG)
Alzheimer’s disease (AD)
β-site amyloid precursor protein cleaving enzyme (BACE-1) inhibitor
TASTPM mice
Online Access:https://www.mdpi.com/1422-0067/21/23/9072

Internet

https://www.mdpi.com/1422-0067/21/23/9072

Similar Items