Global Patterns of Tissue-Specific Alternative Polyadenylation in Drosophila

We analyzed the usage and consequences of alternative cleavage and polyadenylation (APA) in Drosophila melanogaster by using >1 billion reads of stranded mRNA-seq across a variety of dissected tissues. Beyond demonstrating that a majority of fly transcripts are subject to APA, we observed broad...

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Bibliographic Details
Main Authors: Peter Smibert, Pedro Miura, Jakub O. Westholm, Sol Shenker, Gemma May, Michael O. Duff, Dayu Zhang, Brian D. Eads, Joe Carlson, James B. Brown, Robert C. Eisman, Justen Andrews, Thomas Kaufman, Peter Cherbas, Susan E. Celniker, Brenton R. Graveley, Eric C. Lai
Format: Article
Language:English
Published: Elsevier 2012-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124712000216