Development of novel parameter for monitoring of malignant melanoma progression

Objective: Increasing HIFs in malignant melanoma, the highly aggressive skin tumour, results in the stimulation of invasiveness. Increased HIF-1α fallouts in inhibition of the activity of some mitochondrial enzymes and leads to preference of cytosol energetic metabolism. Increase of aerobic glycolys...

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Bibliographic Details
Main Authors: Ivana Špaková, Miroslava Rabajdová, Katarína Dubayová, Vladimíra Nagyová, Martina Bago Pilátová, Mária Mareková
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Practical Laboratory Medicine
Subjects:
VDR
Online Access:http://www.sciencedirect.com/science/article/pii/S2352551720301451