Development of novel parameter for monitoring of malignant melanoma progression
Objective: Increasing HIFs in malignant melanoma, the highly aggressive skin tumour, results in the stimulation of invasiveness. Increased HIF-1α fallouts in inhibition of the activity of some mitochondrial enzymes and leads to preference of cytosol energetic metabolism. Increase of aerobic glycolys...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-11-01
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Series: | Practical Laboratory Medicine |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352551720301451 |