The role of microglial inflammasome activation in pyroptotic cell death following penetrating traumatic brain injury

The role of microglial inflammasome activation in pyroptotic cell death following penetrating traumatic brain injury

Abstract Background Traumatic brain injury remains a significant cause of death and disability in the USA. Currently, there are no effective therapies to mitigate disability except for surgical interventions necessitating a need for continued research into uncovering novel therapeutic targets. In a...

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Bibliographic Details
Main Authors: Stephanie W. Lee, Juan Pablo de Rivero Vaccari, Jessie S. Truettner, W. Dalton Dietrich, Robert W. Keane
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Journal of Neuroinflammation
Subjects:
Inflammasome
ASC
Pyroptosis
Microglia
Infiltrating leukocytes
Traumatic brain injury
Online Access:http://link.springer.com/article/10.1186/s12974-019-1423-6

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http://link.springer.com/article/10.1186/s12974-019-1423-6

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