Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma.

Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma.

The contribution of innate immunity to immunosurveillance of the oncogenic Human Herpes Virus 8 (HHV8) has not been studied in depth. We investigated NK cell phenotype and function in 70 HHV8-infected subjects, either asymptomatic carriers or having developed Kaposi's sarcoma (KS). Our results...

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Bibliographic Details
Main Authors: Stéphanie Dupuy, Marion Lambert, David Zucman, Siméon-Pierre Choukem, Sara Tognarelli, Cécile Pages, Céleste Lebbé, Sophie Caillat-Zucman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3257307?pdf=render

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http://europepmc.org/articles/PMC3257307?pdf=render

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