Effect of pirfenidone on wound healing in lung transplant patients

Abstract Background The drug pirfenidone has been shown to slow the progression and decrease mortality of idiopathic pulmonary fibrosis (IPF). Its exact mechanism is unknown, but it likely inhibits pro-fibrotic cytokine transforming growth factor beta, a known contributor to wound healing. We evalua...

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Bibliographic Details
Main Authors: Amber Mortensen, Lauren Cherrier, Rajat Walia
Format: Article
Language:English
Published: PAGEPress Publications 2018-06-01
Series:Multidisciplinary Respiratory Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40248-018-0129-4