Blocking core fucosylation of epidermal growth factor (EGF) receptor prevents peritoneal fibrosis progression

Blocking core fucosylation of epidermal growth factor (EGF) receptor prevents peritoneal fibrosis progression

Objective Peritoneal fibrosis (PF) ultimately causes ultrafiltration failure and peritoneal dialysis (PD) termination, but there are few effective therapies for it. Core fucosylation, which is catalyzed by α1,6-fucosyltransferase (Fut8) in mammals, may play a crucial role in PF development. This stu...

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Bibliographic Details
Main Authors: Changqing Yu, Ning Yang, Weidong Wang, Xiangning Du, Qingzhu Tang, Hongli Lin, Longkai Li
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Renal Failure
Subjects:
core fucosylation
epidermal growth factor receptor
peritoneal fibrosis
peritoneal dialysis
Online Access:http://dx.doi.org/10.1080/0886022X.2021.1918557

Internet

http://dx.doi.org/10.1080/0886022X.2021.1918557

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