Rapamycin Protects from Type-I Peritoneal Membrane Failure Inhibiting the Angiogenesis, Lymphangiogenesis, and Endo-MT

Rapamycin Protects from Type-I Peritoneal Membrane Failure Inhibiting the Angiogenesis, Lymphangiogenesis, and Endo-MT

Preservation of peritoneal membrane (PM) is essential for long-term survival in peritoneal dialysis (PD). Continuous presence of PD fluids (PDF) in the peritoneal cavity generates chronic inflammation and promotes changes of the PM, such as fibrosis, angiogenesis, and lymphangiogenesis. Mesothelial-...

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Bibliographic Details
Main Authors: Guadalupe Tirma González-Mateo, Anna Rita Aguirre, Jesús Loureiro, Hugo Abensur, Pilar Sandoval, José Antonio Sánchez-Tomero, Gloria del Peso, José Antonio Jiménez-Heffernan, Vicente Ruiz-Carpio, Rafael Selgas, Manuel López-Cabrera, Abelardo Aguilera, Georgios Liappas
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/989560

Internet

http://dx.doi.org/10.1155/2015/989560

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