Cytokine profiles in early rejection following OKT3 treatment in liver transplant patients

OKT3, a murine monoclonal antibody specific to the human CD3 complex, induces immunosuppression by depletion of T cells. Administration of OKT3 results in significant release of proinflammatory cytokines, such as TNFα and IL1β. Liver recipients who experience rejection within 3 weeks after transplan...

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Bibliographic Details
Main Authors: Sasan Roayaie, Patricia A. Sheiner, Sukru Emre, Steven Guy, Myron E. Schwartz, Peter Boros, Charles M. Miller
Format: Article
Language:English
Published: Hindawi Limited 2000-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1080/09629350020002877