Similarities in Gene Expression Profiles during In Vitro Aging of Primary Human Embryonic Lung and Foreskin Fibroblasts

Replicative senescence is of fundamental importance for the process of cellular aging, since it is a property of most of our somatic cells. Here, we elucidated this process by comparing gene expression changes, measured by RNA-seq, in fibroblasts originating from two different tissues, embryonic lun...

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Bibliographic Details
Main Authors: Shiva Marthandan, Steffen Priebe, Mario Baumgart, Marco Groth, Alessandro Cellerino, Reinhard Guthke, Peter Hemmerich, Stephan Diekmann
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/731938