TET1 Directs Chondrogenic Differentiation by Regulating SOX9 Dependent Activation of Col2a1 and Acan In Vitro

ABSTRACT Skeletal development is a tightly orchestrated process in which cartilage and bone differentiation are intricately intertwined. Recent studies have highlighted the contribution of epigenetic modifications and their writers to skeletal development. Methylated cytosine (5mC) can be oxidized t...

Full description

Bibliographic Details
Main Authors: Piera Smeriglio, Fiorella Carla Grandi, Sarah Elizabeth Brook Taylor, Antoine Zalc, Nidhi Bhutani
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:JBMR Plus
Subjects:
Online Access:https://doi.org/10.1002/jbm4.10383