EGF Receptor-Dependent Mechanism May be Involved in the Tamm–Horsfall Glycoprotein-Enhanced PMN Phagocytosis via Activating Rho Family and MAPK Signaling Pathway

EGF Receptor-Dependent Mechanism May be Involved in the Tamm–Horsfall Glycoprotein-Enhanced PMN Phagocytosis via Activating Rho Family and MAPK Signaling Pathway

Our previous studies showed that urinary Tamm–Horsfall glycoprotein (THP) potently enhanced polymorphonuclear neutrophil (PMN) phagocytosis. However, the domain structure(s), signaling pathway and the intracellular events responsible for THP-enhanced PMN phagocytosis remain to be elucidated. THP was...

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Bibliographic Details
Main Authors: Ko-Jen Li, Sue-Cien Siao, Cheng-Han Wu, Chieh-Yu Shen, Tsai-Hung Wu, Chang-Youh Tsai, Song-Chou Hsieh, Chia-Li Yu
Format: Article
Language:English
Published: MDPI AG 2014-01-01
Series:Molecules
Subjects:
Tamm-Horsfall glycoprotein
phagocytosis
EGF-like domains
Rho family
MAP kinase
Online Access:http://www.mdpi.com/1420-3049/19/1/1328

Internet

http://www.mdpi.com/1420-3049/19/1/1328

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