Kinase Inhibitory Activities and Molecular Docking of a Novel Series of Anticancer Pyrazole Derivatives

A series of novel 1,3,4-triarylpyrazoles containing different heterocycles has been prepared, characterized and screened for their in vitro antiproliferative activity against HePG-2, MCF-7, PC-3, A-549 and HCT-116 cancer cell lines. The biological results revealed that compound <b>6</b>...

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Bibliographic Details
Main Authors: Eman S. Nossier, Somaia S. Abd El-Karim, Nagy M. Khalifa, Ali S. El-Sayed, Emad S. I. Hassan, Salwa M. El-Hallouty
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/23/12/3074