Serial histopathological examination of the lungs of mice infected with influenza A virus PR8 strain.

Avian influenza H5N1 and pandemic (H1N1) 2009 viruses are known to induce viral pneumonia and subsequent acute respiratory distress syndrome (ARDS) with diffuse alveolar damage (DAD). The mortality rate of ARDS/DAD is extremely high, at approximately 60%, and no effective treatment for ARDS/DAD has...

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Bibliographic Details
Main Authors: Masaya Fukushi, Tateki Ito, Teruaki Oka, Toshio Kitazawa, Tohru Miyoshi-Akiyama, Teruo Kirikae, Makoto Yamashita, Koichiro Kudo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3118813?pdf=render