Serum IgG anti-SARS-CoV-2 Binding Antibody Level Is Strongly Associated With IgA and Functional Antibody Levels in Adults Infected With SARS-CoV-2

Serum IgG anti-SARS-CoV-2 Binding Antibody Level Is Strongly Associated With IgA and Functional Antibody Levels in Adults Infected With SARS-CoV-2

BackgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in December 2019 in Wuhan, China, and then rapidly spread causing an unprecedented pandemic. A robust serological assay is needed to evaluate vaccine candidates and better understand the epidemiology of coronav...

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Bibliographic Details
Main Authors: Xunyan Ye, Laura S. Angelo, Erin G. Nicholson, Obinna P. Iwuchukwu, Wanderson Cabral de Rezende, Anubama Rajan, Letisha O. Aideyan, Trevor J. McBride, Nanette Bond, Patricia Santarcangelo, Yolanda J. Rayford, Laura Ferlic-Stark, Sonia Fragoso, Zoha Momin, Hongbing Liu, Khanghy Truong, Brianna Lopez, Margaret E. Conner, Andrew P. Rice, Jason T. Kimata, Vasanthi Avadhanula, Pedro A. Piedra
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
COVID-19
serology
human serum
binding antibody
functional antibody
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.693462/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.693462/full

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