Immature Dentate Granule Cells Require Ntrk2/Trkb for the Formation of Functional Hippocampal Circuitry

Immature Dentate Granule Cells Require Ntrk2/Trkb for the Formation of Functional Hippocampal Circuitry

Summary: Early in brain development, impaired neuronal signaling during time-sensitive windows triggers the onset of neurodevelopmental disorders. GABA, through its depolarizing and excitatory actions, drives early developmental events including neuronal circuit formation and refinement. BDNF/TrkB s...

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Bibliographic Details
Main Authors: Sylvia Badurek, Marilena Griguoli, Aman Asif-Malik, Barbara Zonta, Fei Guo, Silvia Middei, Laura Lagostena, Maria Teresa Jurado-Parras, Thomas H. Gillingwater, Agnès Gruart, José María Delgado-García, Enrico Cherubini, Liliana Minichiello
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:iScience
Subjects:
Genetics
Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220302637

Internet

http://www.sciencedirect.com/science/article/pii/S2589004220302637

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