Overexpression of iASPP is required for autophagy in response to oxidative stress in choriocarcinoma

Abstract Background Gestational trophoblastic disease (GTD) is a heterogeneous group of diseases developed from trophoblasts. ASPP (Ankyrin-repeat, SH3-domain and proline-rich region containing protein) family proteins, ASPP1 and ASPP2, have been reported to be dysregulated in GTD. They modulate p53...

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Bibliographic Details
Main Authors: Ka-Kui Chan, Esther Shuk-Ying Wong, Ivy Tsz-Lo Wong, Claire Ling-Yang Cheung, Oscar Gee-Wan Wong, Hextan Yuen-Sheung Ngan, Annie Nga-Yin Cheung
Format: Article
Language:English
Published: BMC 2019-10-01
Series:BMC Cancer
Online Access:http://link.springer.com/article/10.1186/s12885-019-6206-z