Overexpression of <i>Kif1A</i> in the Developing <i>Drosophila</i> Heart Causes Valvar and Contractility Defects: Implications for Human Congenital Heart Disease

Left-sided congenital heart defects (CHDs) are among the most common forms of congenital heart disease, but a disease-causing gene has only been identified in a minority of cases. Here, we identified a candidate gene for CHDs, <i>KIF1A</i>, that was associated with a chromosomal balanced...

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Bibliographic Details
Main Authors: Takeshi Akasaka, Karen Ocorr, Lizhu Lin, Georg Vogler, Rolf Bodmer, Paul Grossfeld
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
Online Access:https://www.mdpi.com/2308-3425/7/2/22