Ai-lncRNA EGOT enhancing autophagy sensitizes paclitaxel cytotoxicity via upregulation of ITPR1 expression by RNA-RNA and RNA-protein interactions in human cancer

Ai-lncRNA EGOT enhancing autophagy sensitizes paclitaxel cytotoxicity via upregulation of ITPR1 expression by RNA-RNA and RNA-protein interactions in human cancer

Abstract Background The biology function of antisense intronic long noncoding RNA (Ai-lncRNA) is still unknown. Meanwhile, cancer patients with paclitaxel resistance have limited therapeutic options in the clinic. However, the potential involvement of Ai-lncRNA in paclitaxel sensitivity remains uncl...

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Bibliographic Details
Main Authors: Shouping Xu, Peiyuan Wang, Jian Zhang, Hao Wu, Shiyao Sui, Jinfeng Zhang, Qin Wang, Kun Qiao, Weiwei Yang, Hongbiao Xu, Da Pang
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Molecular Cancer
Subjects:
Ai-lncRNA
EGOT
ITPR1
Paclitaxel
Autophagy
Cancer
Online Access:http://link.springer.com/article/10.1186/s12943-019-1017-z

Internet

http://link.springer.com/article/10.1186/s12943-019-1017-z

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