Binding and intracellular trafficking of lipoprotein lipase and triacylglycerol-rich lipoproteins by liver cells

The cellular mechanisms and pathways by which lipoprotein lipase (LPL) enhances the binding and uptake of lipoproteins remains unknown. Confocal and immunoelectron microscopy demonstrated that primary binding of bovine LPL (bLPL) occurs at the microvilli surface of HepG2 cells and hepatocytes. Inter...

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Bibliographic Details
Main Authors: Ricardo P. Casaroli-Marano, Raquel García, Elisabet Vilella, Gunilla Olivecrona, Manuel Reina, Senén Vilaró
Format: Article
Language:English
Published: Elsevier 1998-04-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520325670