Development, Maintenance, and Reversal of Multiple Drug Resistance: At the Crossroads of TFPI1, ABC Transporters, and HIF1

Early detection and improved therapies for many cancers are enhancing survival rates. Although many cytotoxic therapies are approved for aggressive or metastatic cancer; response rates are low and acquisition of de novo resistance is virtually universal. For decades; chemotherapeutic treatments for...

Full description

Bibliographic Details
Main Authors: Terra Arnason, Troy Harkness
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/7/4/0877