Biomechanical Cues Direct Valvulogenesis

The vertebrate embryonic heart initially forms with two chambers, a ventricle and an atrium, separated by the atrioventricular junction. Localized genetic and biomechanical information guides the development of valves, which function to ensure unidirectional blood flow. If the valve development proc...

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Bibliographic Details
Main Authors: Neha Ahuja, Paige Ostwald, David Bark, Deborah Garrity
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
Online Access:https://www.mdpi.com/2308-3425/7/2/18