Efficient Construction and Effective Screening of Synthetic Domain Antibody Libraries

Phage display is a powerful technique for drug discovery in biomedical research in particular for antibody libraries. But, several technical challenges are associated with the selection process. For instance, during the panning step, the successful elution of the phages bound to the antigen is criti...

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Bibliographic Details
Main Authors: Arghavan Solemani Zadeh, Alissa Grässer, Heiko Dinter, Maximilian Hermes, Katharina Schindowski
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Methods and Protocols
Subjects:
Online Access:https://www.mdpi.com/2409-9279/2/1/17