Prolonged Aβ treatment leads to impairment in the ability of primary cortical neurons to maintain K<sup>+ </sup>and Ca<sup>2+ </sup>homeostasis

<p>Abstract</p> <p>Background</p> <p>Alzheimer's disease (AD) is a progressive neurodegenerative disease, characterised by the formation of insoluble amyloidogenic plaques and neurofibrillary tangles. Beta amyloid (Aβ) peptide is one of the main constituents in Aβ...

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Bibliographic Details
Main Authors: Shabala Lana, Howells Claire, West Adrian K, Chung Roger S
Format: Article
Language:English
Published: BMC 2010-08-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/5/1/30