Prolonged Aβ treatment leads to impairment in the ability of primary cortical neurons to maintain K<sup>+ </sup>and Ca<sup>2+ </sup>homeostasis
<p>Abstract</p> <p>Background</p> <p>Alzheimer's disease (AD) is a progressive neurodegenerative disease, characterised by the formation of insoluble amyloidogenic plaques and neurofibrillary tangles. Beta amyloid (Aβ) peptide is one of the main constituents in Aβ...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2010-08-01
|
Series: | Molecular Neurodegeneration |
Online Access: | http://www.molecularneurodegeneration.com/content/5/1/30 |