Lyn facilitates glioblastoma cell survival under conditions of nutrient deprivation by promoting autophagy.

Lyn facilitates glioblastoma cell survival under conditions of nutrient deprivation by promoting autophagy.

Members of the Src family kinases (SFK) can modulate diverse cellular processes, including division, death and survival, but their role in autophagy has been minimally explored. Here, we investigated the roles of Lyn, a SFK, in promoting the survival of human glioblastoma tumor (GBM) cells in vitro...

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Bibliographic Details
Main Authors: Wei Michael Liu, Ping Huang, Niladri Kar, Monica Burgett, Gaelle Muller-Greven, Amy S Nowacki, Clark W Distelhorst, Justin D Lathia, Jeremy N Rich, John C Kappes, Candece L Gladson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3732228?pdf=render

Internet

http://europepmc.org/articles/PMC3732228?pdf=render

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