DNA methylation aging clocks: challenges and recommendations

DNA methylation aging clocks: challenges and recommendations

Abstract Epigenetic clocks comprise a set of CpG sites whose DNA methylation levels measure subject age. These clocks are acknowledged as a highly accurate molecular correlate of chronological age in humans and other vertebrates. Also, extensive research is aimed at their potential to quantify biolo...

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Bibliographic Details
Main Authors: Christopher G. Bell, Robert Lowe, Peter D. Adams, Andrea A. Baccarelli, Stephan Beck, Jordana T. Bell, Brock C. Christensen, Vadim N. Gladyshev, Bastiaan T. Heijmans, Steve Horvath, Trey Ideker, Jean-Pierre J. Issa, Karl T. Kelsey, Riccardo E. Marioni, Wolf Reik, Caroline L. Relton, Leonard C. Schalkwyk, Andrew E. Teschendorff, Wolfgang Wagner, Kang Zhang, Vardhman K. Rakyan
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Genome Biology
Online Access:http://link.springer.com/article/10.1186/s13059-019-1824-y

Internet

http://link.springer.com/article/10.1186/s13059-019-1824-y

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