STIM and Orai1 variants in store-operated calcium entry

Store-operated Ca2+ is an ubiquitous mechanism for Ca2+ entry in eukaryotic cells. This route for Ca2+ influx is regulated by the filling state of the intracellular Ca2+ stores communicated to the plasma membrane channels by the proteins of the STIM family, STIM1 and STIM2. Store-dependent, STIM1-mo...

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Bibliographic Details
Main Authors: JUAN ANTONIO ROSADO, Raquel eDiez, Tarik eSmani, Isaac eJardin
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00325/full