Cationic Polybutyl Cyanoacrylate Nanoparticles for DNA Delivery

To enhance the intracellular delivery potential of plasmid DNA using nonviral vectors, we used polybutyl cyanoacrylate (PBCA) and chitosan to prepare PBCA nanoparticles (NPs) by emulsion polymerization and prepared NP/DNA complexes through the complex coacervation of nanoparticles with the DNA. The...

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Bibliographic Details
Main Authors: Jinghua Duan, Yangde Zhang, Wei Chen, Chengrong Shen, Mingmei Liao, Yifeng Pan, Jiwei Wang, Xingming Deng, Jinfeng Zhao
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2009/149254