Metastable Reprogramming State of Single Transcription Factor-Derived Induced Hepatocyte-Like Cells

We previously described the generation of induced hepatocyte-like cells (iHeps) using the hepatic transcription factor Hnf1a together with small molecules. These iHeps represent a hepatic state that is more mature compared with iHeps generated with multiple hepatic factors. However, the underlying m...

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Bibliographic Details
Main Authors: Seon In Hwang, Tae Hwan Kwak, Ji Hyun Kang, Jonghun Kim, Hyunseong Lee, Kee-Pyo Kim, Kinarm Ko, Hans R. Schöler, Dong Wook Han
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2019/6937257