The praziquantel in preschoolers (PIP) trial: study protocol for a phase II PK/PD-driven randomised controlled trial of praziquantel in children under 4 years of age

The praziquantel in preschoolers (PIP) trial: study protocol for a phase II PK/PD-driven randomised controlled trial of praziquantel in children under 4 years of age

Abstract Background Over 200 million individuals worldwide are infected with Schistosoma species, with over half of infections occurring in children. Many children experience first infections early in life and this impacts their growth and development; however praziquantel (PZQ), the drug used world...

Full description

Bibliographic Details
Main Authors: Emily L. Webb, Andrew Edielu, Hannah W. Wu, Narcis B. Kabatereine, Edridah M. Tukahebwa, Alfred Mubangizi, Moses Adriko, Alison M. Elliott, William W. Hope, Patrice A. Mawa, Jennifer F. Friedman, Amaya L. Bustinduy
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Trials
Subjects:
Praziquantel
Preschool
Children
Intestinal schistosomiasis
Schistosoma mansoni
Schistosoma japonicum
Online Access:https://doi.org/10.1186/s13063-021-05558-1

Internet

https://doi.org/10.1186/s13063-021-05558-1

Similar Items