Comparative proteomic analyses of Duchenne muscular dystrophy and Becker muscular dystrophy muscles: changes contributing to preserve muscle function in Becker muscular dystrophy patients

Comparative proteomic analyses of Duchenne muscular dystrophy and Becker muscular dystrophy muscles: changes contributing to preserve muscle function in Becker muscular dystrophy patients

Abstract Background Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are characterized by muscle wasting leading to loss of ambulation in the first or third decade, respectively. In DMD, the lack of dystrophin hampers connections between intracellular cytoskeleton and cell membr...

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Bibliographic Details
Main Authors: Daniele Capitanio, Manuela Moriggi, Enrica Torretta, Pietro Barbacini, Sara De Palma, Agnese Viganò, Hanns Lochmüller, Francesco Muntoni, Alessandra Ferlini, Marina Mora, Cecilia Gelfi
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Proteomics
Mechanotransduction
Bioenergetics
Duchenne muscular dystrophy
Becker muscular dystrophy
Reactive oxygen species
Online Access:https://doi.org/10.1002/jcsm.12527

Internet

https://doi.org/10.1002/jcsm.12527

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