Longitudinal monitoring of Gaussia and Nano luciferase activities to concurrently assess ER calcium homeostasis and ER stress in vivo.

The endoplasmic reticulum (ER) is essential to many cellular processes including protein processing, lipid metabolism and calcium storage. The ability to longitudinally monitor ER homeostasis in the same organism would offer insight into progressive molecular and cellular adaptations to physiologic...

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Bibliographic Details
Main Authors: Emily S Wires, Mark J Henderson, Xiaokang Yan, Susanne Bäck, Kathleen A Trychta, Molly H Lutrey, Brandon K Harvey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5389830?pdf=render