Chronic Alcoholism and HHV-6 Infection Synergistically Promote Neuroinflammatory Microglial Phenotypes in the <i>Substantia Nigra</i> of the Adult Human Brain

Chronic Alcoholism and HHV-6 Infection Synergistically Promote Neuroinflammatory Microglial Phenotypes in the <i>Substantia Nigra</i> of the Adult Human Brain

Both chronic alcoholism and human herpesvirus-6 (HHV-6) infection have been identified as promoters of neuroinflammation and known to cause movement-related disorders. <i>Substantia Nigra</i> (SN), the dopaminergic neuron-rich region of the basal ganglia, is involved in regulating motor...

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Bibliographic Details
Main Authors: Nityanand Jain, Marks Smirnovs, Samanta Strojeva, Modra Murovska, Sandra Skuja
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Biomedicines
Subjects:
microglia
neuroinflammation
chronic alcoholism
HHV-6
<i>Substantia Nigra</i>
Online Access:https://www.mdpi.com/2227-9059/9/9/1216

Internet

https://www.mdpi.com/2227-9059/9/9/1216

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