Identification of a bacterial-like HslVU protease in the mitochondria of Trypanosoma brucei and its role in mitochondrial DNA replication.

ATP-dependent protease complexes are present in all living organisms, including the 26S proteasome in eukaryotes, Archaea, and Actinomycetales, and the HslVU protease in eubacteria. The structure of HslVU protease resembles that of the 26S proteasome, and the simultaneous presence of both proteases...

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Bibliographic Details
Main Authors: Ziyin Li, Megan E Lindsay, Shawn A Motyka, Paul T Englund, Ching C Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2277460?pdf=render