Reproductive characteristics are associated with gene-specific promoter methylation status in breast cancer

Reproductive characteristics are associated with gene-specific promoter methylation status in breast cancer

Abstract Background Reproductive characteristics are well-established risk factors for breast cancer, but the underlying mechanisms are not fully resolved. We hypothesized that altered DNA methylation, measured in tumor tissue, could act in concert with reproductive factors to impact breast carcinog...

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Bibliographic Details
Main Authors: Lauren E. McCullough, Lindsay J. Collin, Kathleen Conway, Alexandra J. White, Yoon Hee Cho, Sumitra Shantakumar, Mary Beth Terry, Susan L. Teitelbaum, Alfred I. Neugut, Regina M. Santella, Jia Chen, Marilie D. Gammon
Format: Article
Language:English
Published: BMC 2019-09-01
Series:BMC Cancer
Subjects:
Breast Cancer
Epidemiology
Epigenetics
Reproductive characteristics
DNA methylation
Online Access:http://link.springer.com/article/10.1186/s12885-019-6120-4

Internet

http://link.springer.com/article/10.1186/s12885-019-6120-4

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