Efficacy and safety of three antiretroviral regimens for initial treatment of HIV-1: a randomized clinical trial in diverse multinational settings.

<h4>Background</h4>Antiretroviral regimens with simplified dosing and better safety are needed to maximize the efficiency of antiretroviral delivery in resource-limited settings. We investigated the efficacy and safety of antiretroviral regimens with once-daily compared to twice-daily do...

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Main Authors: Thomas B Campbell, Laura M Smeaton, N Kumarasamy, Timothy Flanigan, Karin L Klingman, Cynthia Firnhaber, Beatriz Grinsztejn, Mina C Hosseinipour, Johnstone Kumwenda, Umesh Lalloo, Cynthia Riviere, Jorge Sanchez, Marineide Melo, Khuanchai Supparatpinyo, Srikanth Tripathy, Ana I Martinez, Apsara Nair, Ann Walawander, Laura Moran, Yun Chen, Wendy Snowden, James F Rooney, Jonathan Uy, Robert T Schooley, Victor De Gruttola, James Gita Hakim, PEARLS study team of the ACTG
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1001290