Influence of the TGF-β Superfamily on Osteoclasts/Osteoblasts Balance in Physiological and Pathological Bone Conditions

Influence of the TGF-β Superfamily on Osteoclasts/Osteoblasts Balance in Physiological and Pathological Bone Conditions

The balance between bone forming cells (osteoblasts/osteocytes) and bone resorbing cells (osteoclasts) plays a crucial role in tissue homeostasis and bone repair. Several hormones, cytokines, and growth factors—in particular the members of the TGF-β superfamily such as the bone morphogenetic protein...

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Bibliographic Details
Main Authors: Jessica Jann, Suzanne Gascon, Sophie Roux, Nathalie Faucheux
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
bone morphogenetic proteins
osteoclastogenesis
osteogenic differentiation
smad signaling pathway
RANKL
Online Access:https://www.mdpi.com/1422-0067/21/20/7597

Internet

https://www.mdpi.com/1422-0067/21/20/7597

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